Mitchell Reff,Kandasamy Hariharan,MacLaren Ann,Sisk William
申请号：
US12593282
公开号：
US20130183288A1
申请日:
2008.03.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides non-fucosylated therapeutic antibodies. More particularly, the invention provides non-fucosylated anti-CD20, anti-CD23 and anti-CD80 antibodies, which show enhanced antibody effector functions. Also provided are cells expressing the non-fucosylated antibodies and therapeutic methods using the non-fucosylated antibodies.
