CASTAGNER BASTIEN,LEROUX JEAN-CHRISTOPHE,IVARSSON MATTIAS,SCHNEIDER GISBERT,PRATSINIS ANNA
申请号：
NZ62418912
公开号：
NZ624189A
申请日:
2012.09.28
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Provided are poly-phosphate, polysulfate or mixed polyphosphate/sulfate derivatives of six-membered cyclic polyol compounds, of general formulae (1) and (15), wherein the variables are as defined in the specification. The compounds are analogues of inositol hexakisphosphate (IP6)/phytic acid. An example of the compounds is myo-inositol-pentakisphosphate-2-PEG(400). The compounds are enteric activators of Clostridium difficile toxin. The compounds are useful in the treatment of Clostridium difficile infection.
