The present invention provides expression vectors encoding double stranded RNAs that target certain plant genes required for maintenance of parasitic nematode infection, nematode-resistant transgenic plants that express such double-stranded RNAs, and methods associated therewith. The targeted plant gene is a GLABRA-like gene, a homeodomain-like gene, a trehalose-6-phosphate phosphatase-like gene, an unknown gene having at least 80% homology to SEQ ID NO:16, a ringH2 finger-like gene, a zinc finger-like gene, or a MIOX-like gene.
