Yoon Jin Lee,Yun-Sil Lee,Hae-June Lee,Seo-Hyun Choi,Kyeng-Jung Kim
申请号：
US13817738
公开号：
US20130184336A1
申请日:
2011.08.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides a pharmaceutical composition for suppressing angiogenesis, containing heat shock protein 27 (HSP27) or a nucleic acid encoding HSP27. In addition, the present invention provides a pharmaceutical composition for treating cancer, containing HSP27 or a nucleic acid encoding HSP27. Additionally, the present invention provides a method of suppressing the in vitro growth of endothelial cells using HSP27. Further, the present invention provides a method of screening an active material for suppressing angiogenesis or an active material for treating cancer, comprising the following steps: processing endothelial cell lines into samples, respectively measuring the content of HSP27 in an endothelial cell line and selecting the sample in which the content of HSP27 in an endothelial cell line is increased compared with a control group.
