NOUVEAUX DERIVES DE BENZIMIDAZOLE COMME INHIBITEURS DE LA FAMILLE DES KINASES TEC

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专利权人:

INC.;GB005

发明人:

LAURENT, ALAIN,ROSE, YANNICK,MORRIS, STEPHEN J.

申请号：

CA3037971

公开号：

CA3037971A1

申请日:

2016.09.22

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention relates to a novel family of covalent kinases inhibitors. Compounds of this class have been found to have inhibitory activity against members of the Tec kinase family, particularly ITK, BTK, BMX, Tec and/or RLK. The present invention is directed to a compound of Formula I or pharmaceutically acceptable salt, solvate, solvate of salt, stereoisomer, tautomer, isotope, prodrug, complex or biologically active metabolite thereof, and its use in therapy.

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