您的位置: 首页 > 农业专利 > 详情页

PHARMACEUTICAL FORMULATIONS CONTAINING 3-(4-CINNAMYL-L-PIPERAZINYL) AMINO DERIVATIVES OF 3-FORMYLRIFAMYCIN SV AND 3-FORMYLRIFAMYCIN S AND A PROCESS OF THEIR PREPARATION
专利权人:
ADIPHARM; EAD
发明人:
KONSTANTINOVA, RUMYANA GUEORGUIEVA,NINOV, KIRIL ASENOV,APOSTOLOVA-DIMOVA, VELICHKA LLIEVA,STEFANOVA, EVTIMIA IVANOVA,KOYTCHEV, ROSSEN KRUMOV
申请号:
EP13829445
公开号:
EP2882435A4
申请日:
2013.08.09
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention related to a process of preparation of pharmaceutically acceptable formulations containing as active substance 3-(4-cinnamyl-1-piperazinyl)-amino derivatives of 3-formylrifamycine SV and 3-formylrifamycine S, which possess high activity against Gram-positive and Gram-negative microorganisms, as well as against tuberculous micobacteria (including atypical and rifamycin resistant), and to a method for the preparation of 3-(4-cinnamyl-1-piperazinyl)-amino derivatives of 3-formylrifamycine SV and 3-formylrifamycine S. The method for the preparation of pharmaceutical compositions is readily feasible, and does not require special equipment for its implementation. The process for preparing the compounds is characterized by high yield and purity, using an environmental clean solvent-ethanol and water in the preparation and isolation of substances, and the absence of residual organic solvents in the final product.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充