HDAC-INHIBITOREN, ALLEIN ODER IN KOMBINATION MIT BTK-INHIBITOREN, ZUR BEHANDLUNG VON CHRONISCHER LYMPHOZYTISCHER LEUKÄMIE

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专利权人:

Acetylon Pharmaceuticals, Inc.;H. Lee Moffitt Cancer Center And Research Institute, Inc.

发明人:

JONES, Simon, S.,QUAYLE, Steven, N.,SAHAKIAN, Eva,IBARZ, Javier, Pinilla

申请号：

EP17786584

公开号：

EP3445364A4

申请日:

2017.04.19

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed are histone deacetylase (HDAC) inhibitors, or combinations comprising an HDAC inhibitor and a Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of chronic lymphocytic leukemia in a subject in need thereof. Also provided herein are methods for treating chronic lymphocytic leukemia in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an HDAC inhibitor, or a combination comprising an HDAC inhibitor and a BTK inhibitor. Other related methods are disclosed.

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中国工程科技知识中心

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http://www.ckcest.cn/home/