DR GIRIDHARAN BUPESH,DR T SHIVA VIJAYAKUMAR,DR CHINNAIAH AMUTHA,DR CHITRALEKHA SAIKUMAR,DR P SUBRAMANIAN
申请号：
IN201741023237
公开号：
IN201741023237A
申请日:
2017.07.01
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention shall disclose a novel biocompatible sustained-release nano-particle pharmaceutical formulation exhibiting antimicrobial activity against multidrug resistance bacteria with enhanced bio availability and therapeutic efficacy. The formulation of the present invention comprises of therapeutically effective amount of peptide antibiotics Pleurocidin like peptide PLP encapsulated in N-Succinyl Chitosan nanoparticle. The peptide antibiotics Pleurocidin like peptide PLP is isolated from epidermis of Clarias batrachus. The encapsulation of peptide antibiotics Pleurocidin like peptide PLP in N-Succinyl Chitosan nanoparticle was done using NSC nanoparticle by immobilization technique through micro syringe
