Jeremy BARYZA,Keith BOWMAN,Andrew GEALL,Tanzina LABONTE,Cameron LEE,Chandra VARGEESE,Laura WEST,Junping ZHAO
申请号:
US14197124
公开号:
US20140309277A1
申请日:
2014.03.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I).The invention also relates to compositions and uses for stealth lipids of formula (XI).Also provided are processes for making such compounds, compositions, and formulations, plus methods and uses of such compounds, compositions, and formulations to deliver biologically active agents to cells and/or tissues.