INC.;ARRAY BIOPHARMA;ARRAY BIOPHARMA, INC.;VENTIRX PHARMACEUTICALS, INC.
发明人:
ROBERT HERSHBERG,JAMES JEFFRY HOWBERT,LAURENCE E. BURGESS,HONG WOON YANG
申请号:
PT12734770
公开号:
PT2663550T
申请日:
2012.01.12
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
Provided are benzazepine derivatives useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The benzazepine derivatives have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.