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КОНЪЮГАТ ДЛЯ ФОТОДИНАМИЧЕСКОЙ ДИАГНОСТИКИ ИЛИ ТЕРАПИИ, А ТАКЖЕ СПОСОБ ЕГО ПОЛУЧЕНИЯ
专利权人:
ПАНАКСЕМ КО.; ЛТД. (KR)
发明人:
НА Кун (KR),ЛИ Фанг Юан (KR),БЭ Бёнг Чан (KR)
申请号:
RU2013119911/15
公开号:
RU2013119911A
申请日:
2011.12.21
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A conjugate for photodynamic diagnosis or therapy, wherein the acetylated polysaccharide, biocompatible compound is associated with on the basis ftalotsianina.2. A conjugate for photodynamic diagnosis or therapy according to claim 1, wherein the phthalocyanine-based compound is a phthalocyanine derivative, naphthalocyanine or a derivative thereof containing the center of the structure metalla.3 ion. A conjugate for photodynamic diagnosis or therapy according to claim 2, wherein the central metal ion compounds based on phthalocyanine represents Zn, Cu, Al, Ga, Co, Fe, Ni, P or Cr.4. A conjugate for photodynamic diagnosis or therapy according to claim 1, wherein the phthalocyanine-based compound fluoresces under light of near infrared region and comprises -COOH.5 group. A conjugate for photodynamic diagnosis or therapy according to claim 1, wherein the phthalocyanine-based compound is a compound of the following formula 1: [Formula 1] wherein each R-independently represents a hydrogen atom, a halogen atom, C-alkyl, -COOH, -SOH or a benzene ring unsubstituted or substituted by -COOH or -SOH and wherein M represents Zn, Cu, Al, Ga, Co, Fe, Ni, P or Cr.6. A conjugate for photodynamic diagnosis or therapy according to claim 1, wherein the biocompatible polysaccharide is pullulan, hyaluronic acid, dextran, or chondroitin sulfat.7. A conjugate for photodynamic diagnosis or therapy according to claim 1, wherein the biologically compatible polymer material is additionally connected, aimed at cancer kletki.8. A conjugate for photodynamic diagnosis or therapy according to claim 7, wherein the material aimed at cancer1. Конъюгат для фотодинамической диагностики или терапии, в котором ацетилированный биологически совместимый полисахарид связан с соединением на основе фталоцианина.2. Конъюгат для фотодинамической диагностики или терапии по п.1, в котором соединение на основе фталоцианина представляет собой фталоцианин, его производное, нафталоцианин или его производное, содержа
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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