PROBLEM TO BE SOLVED: To provide a novel collagenase MMP1 and 3 production inhibitor.SOLUTION: A collagenase MMP1 and 3 production inhibitor contains 3HB(R-3-hydroxybutyric acid) as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】新規なコラゲナーゼMMP1及び3の産生抑制剤を提供すること。【解決手段】有効成分として3HB(R-3ヒドロキシ酪酸)を含有するコラゲナーゼMMP1及び3の産生抑制剤。【選択図】なし