There is provided a medicine packaging device that can resolve the problem in which fine mechanical adjustments are needed for changing setting conditions of a packaging part or when the packaging part fails. The medicine packaging device has a device body 3 having an accommodation space 5, a slide unit 8 reciprocally attached to the accommodation space 5 of the device body 3, and a packaging unit 4 removably attached to the slide unit 8. The packaging unit is allowed to package medicines with a package paper 23 by moving the slide unit 8 a packaging position in the accommodation space 5. The packaging unit is moved to a drawn-out position drawn out from the packaging position. The packaging unit is replacable by being moved to a replacement position drawn out from the device body 3.
