Oscar Mario Saavedra,Stephen William Claridge,Lijie Zhan,Franck Raeppel,Arkadii Vaisburg,Stephane Raeppel,Michael Mannion,Frederic Gaudette,Ljubomir Isakovic,Marie-Claude Granger,Naomy Bernstein
申请号：
US11438133
公开号：
US08093264B2
申请日:
2006.05.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention provides compounds of general formula (A)wherein A1 is sulfur, A3 is CH, A2 is CH, D is heterocycle, Z is oxygen, SO0-2 or NR, Ar is phenyl and G is not a ring, and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
