A Variable Angle Surgical Instrument is disclosed and generally comprises: a rail portion including a proximal end, a distal end, and a longitudinal axis extending therebetween a jaw portion operably coupled to the distal end of the rail portion wherein the jaw portion rotates to variable angles relative to the longitudinal axis, and the jaw portion operates between a closed position and an open position to clamp down and remove tissue a locking mechanism operably coupled to the rail portion to lock the jaw portion to an angled position.