A method and devices for mitigating the risk of limb ischemia includesinserting afemoral arterial cannula into a femoral artery of a limb, the femoral arterialcannula having a low-profile balloon to seal the femoral artery. Once in situinthe femoral artery, the femoral arterial cannula balloon is inflated to sealsaidfemoral artery to deliver blood flow in a retrograde direction to said limbwhilesimultaneously delivering systemic arterial blood flow. A femoral venouscannulais also inserted into a femoral vein of said limb, the femoral venous cannulahaving a broad-profile balloon to seal the femoral vein. Once in situ in saidfemoral vein, the femoral venous cannula balloon is inflated to seal thefemoralvein to drain venous blood flow from the limb while simultaneously drainingsystemic venous blood flow.