A degradable iron-based alloy stent comprises an iron-based alloy substrate and a degradable polymer in contact with the surface of the substrate. The weight-average molecular weight of the degradable polymer is in the range of [1, 100]*10 4 , and the polydispersity index of the degradable polymer is in the range of (1.0, 50]. The degradable polymer is selected from a degradable polyamino acid that can generate an acidic amino acid after degradation； or a mixture of the degradable polyamino acid and a degradable polyester, or a copolymer of monomers of the two； or a mixture of the degradable polyamino acid and a degradable polymer that does not generate acidic products after degradation, or a copolymer of the monomers of the two； or a mixture of the degradable polyamino acid, the degradable polyester and the degradable polymer that does not generate acidic products after degradation, or a copolymer of monomers of the three, or a mixture of a copolymer of monomers of any two of the three with the remaining one.
