Composition for the treatment of sexual dysfunction, such as erectile dysfunction, low sexual desire, arousal disorder, and orgasmic disorder in a male or female. The composition includes (i) a therapeutically effective amount of a cannabinoid component that enhances sexual sensitivity and pleasure including at least one of tetrahydrocannabinol and cannabidiol and (ii) a therapeutically effective amount of a sexual response component that increase blood flow to the genital region selected from sildenafil, tadalafil, vardenafil, L-arginine, yohimbe, ginseng, Gingko biloba, horny goat weed, and herbal supplements that increase blood flow to the genital region. The amounts and/or ratio of THC and CBD can be selected depending on age, gender, physical health, and/or psychological condition of the user. The cannabinoid component and the sexual response component interact synergistically to treat various types of human sexual dysfunction.
