Chia-Hung Lee,Wei-Neng Liao,Shih-Hsun Cheng,Jen-Kun Chen,Chung-Shi Yang,Leu-Wei Lo,Yeu-Kuang Hwu,Fong-Sian Lin
申请号：
US13109438
公开号：
US08734844B2
申请日:
2011.05.17
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A method of synthesizing ligand-conjugated gold nanoparticles (AuNPs) is disclosed. The method comprises: a) providing an amine-modified silica particle b) providing a solution comprising Au+3 ions c) suspending the amine-modified silica particle in the solution comprising Au+3 ions d) allowing the Au3+ ions to be adsorbed and/or immobilized onto the surface of the amine-modified silica particle e) exposing the Au3+ ions immobilized onto the surface of the amine-modified silica particle to radiation to obtain bare gold nanoparticles (AuNPs) adsorbed and/or immobilized onto the surface of the amine-modified silica particle, wherein the bare AuNPs are without organic surface modifications and f) reacting a ligand with the bare AuNPs adsorbed and/or immobilized onto the surface of the amine-modified SiNP and thereby obtain ligand-conjugated gold nanoparticles (AuNPs).
