Yi ZHU,Ole OLSEN,Dong XIA,David JELLYMAN,Katrina BYKOVA,Anne-Marie K. ROUSSEAU,Bill BRADY,Blair RENSHAW,Brian KOVACEVICH,Yu LIANG,Zeren GAO
申请号：
US16615117
公开号：
US20200157213A1
申请日:
2018.06.22
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The application provides tri-specific antibody monomers having a N-terminal and a C-terminal, comprising in tandem from the N-terminal to the C-terminal, a first scFv domain at the N-terminal, a Fab domain, a Fc domain, and a second scFv domain at the C-terminal. In one embodiment, the first scFv domain, the Fab domain, and the second scFv domain each has a binding specificity against a different antigen.
