The invention relates to a method for improving the benefit of a therapy or a therapeutic agent to a subject. The method comprises administering to the subject an agent which reduces Fc receptor binding of serum IgG molecules in the subject and subsequently administering said therapy or said therapeutic agent to the subject. The invention also relates to a method for reducing the effect of pathogenic autoantibodies in a subject, the method comprising (a) administering to the subject an agent which reduces Fc receptor binding of serum IgG molecules in the subject and optionally (b) subsequently subjecting the subject to a treatment which removes endogenous autoantibodies. The invention also relates to a kit for carrying out a method of the invention.La invencion se refiere a un metodo para mejorar el beneficio de una terapia o un agente terapeutico para un sujeto. El metodo comprende administrar al sujeto un agente que reduce la union al receptor Fc de moleculas de IgG en suero en el sujeto y administrar posteriormente dicha terapia o dicho agente terapeutico al sujeto. La invencion se refiere tambien a un metodo para reducir el efecto de autoanticuerpos patogenos en un sujeto, comprendiendo el metodo (a) administrar al sujeto un agente que reduce la union al receptor de Fc de moleculas de IgG en suero en el sujeto y opcionalmente (b) someter al sujeto a un tratamiento que elimina autoanticuerpos endogenos. La invencion se refiere tambien a un kit para llevar a cabo un metodo de la invencion.