ANTICORPS MONOCLONAUX ANTI-POLY-N-ACETYL GLUCOSAMINE (PNAG) ET UTILISATIONS ASSOCIEES DANS LA PREVENTION OU LE TRAITEMENT D'UNE INFECTION BACTERIENNE EXPRIMANT PNAG
REY, ASTRID,CANTALLOUBE, CATHY,LI, MENG,TANG, LEI,VLOCK, DANIEL
申请号:
CA2882889
公开号:
CA2882889A1
申请日:
2013.08.22
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Provided are methods for the treatment or prevention of microbial infections (e.g., bacterial infection) in which the underlying pathology involves a PNAG-expressing microbe (e.g., PNAG-expressing bacteria). The methods of the invention generally involve administering to the subject an effective amount of an antibody that specifically binds to PNAG. Such methods are particularly useful for the treatment of nosocomial staphylococcus (e.g., S. epidermidis and S. aureus) infections.