Use of a nickel complex in preparing drugs for relieving inflammation is disclosed. The nickel complex having at least one of a structural formula (I) and a structural formula (II):wherein, L is a solvent molecule. The nickel complex has a similar reactivity with the active site of nickel-containing superoxide dismutase (NiSOD), which could remove reactive oxygen species, such that the nickel complex could be used to prepare drugs for relieving inflammation.
