A diagnostic method includes receiving data comprising a series of heartbeat intervals acquired from a patient (22). A first type of computation, selected from a group of computation types consisting of time-domain analysis (82), frequency-domain analysis (84), and nonlinear fractal analysis (86), is applied to the data in order to compute a first measure of heart rate variability (HRV) of the patient. A second type of computation, selected from the group and different from the first type, is applied to the data in order to compute a second measure of the HRV of the patient. At least the first and second measures are combined so as to derive a parameter indicative of a condition of cardiac health of the patient.
