This Hair Ming Gong Open Novel pyrimidine derivative of formula (I), its Men System Prepare method, its Men control Treatment Redundant natural disposition disease, the purposes of inflammatory and Mian Yi Xi System illness and Drug Wu Group comprising its Men with what as Drug object and close object.本發明公開了式(I)的新嘧啶衍生物,它們的製備方法、它們作爲藥物用於治療贅生性疾病、炎性和免疫系統病症的用途和包含它們的藥物組合物。