NAPADISYLATE SALT OF 5-(2-{[6-(2,2-DIFLUORO-2-PHENYLETHOXY) HEXYL]AMINO}-1-HYDROXYETHYL)-8-HYDROXYQUINOLIN-2(1H)-ONE AS AGONIST OF THE BETA 2 ADRENERGIC RECEPTOR
PUIG DURAN CARLOS,푸이그 두란 카를로스,MOYES VALLS ENRIQUE,모예스 발스 엔리케
申请号：
KR1020147032769
公开号：
KR1020140140651A
申请日:
2008.02.08
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
The present disclosure relates to crystalline monoapadisylate and/or heminapadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, and pharmaceutically acceptable solvates thereof. The present disclosure also relates to pharmaceutical compositions comprising the crystalline monoapadisylate and/or heminapadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, and to methods of treatment comprising these pharmaceutical compositions.본 발명은 5-(2-{[6-(2,2-디플루오로-2-페닐에톡시)헥실]아미노}-1-히드록시에틸)-8-히드록시퀴놀린-2(1H)-온의 결정질 모노나파디실레이트 및/또는 헤미나파디실레이트 염 및 이의 약학적으로 허용가능한 용매화물에 관한 것이다.
