Processes for the preparation of (3S,4R)-3,ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
Ayman Allian,Jayanthy Jayanth,Ben Klünder,Mohamed-Eslam F. Mohamed,Ahmed A. Othman,Patrick J. Marroum,Peter T. Mayer
申请号：
US16453684
公开号：
US10519164B2
申请日:
2019.06.26
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.
