Institute of Pharmacology Academy of Military Sciences P. L.A. China
发明人:
Wu ZHONG,Meiyan YANG,Wei GONG,Yuli WANG,Chunsheng GAO,Xinbo ZHOU,Song LI
申请号：
US16317942
公开号：
US20190358203A1
申请日:
2017.07.04
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a pharmaceutical composition, comprising Tecovirimat, cyclodextrin and an additive, and optionally a pharmaceutically acceptable excipient. The present invention also relates to a method for preparing the pharmaceutical composition. The composition improves the solubility of Tecovirimat in water by using cyclodextrin and meglumine in combination, as compared with the solubility of Tecovirimat in water by using cyclodextrin or meglumine alone.
