This Hair is bright to be related to Yi Seed Tong Time with thrombus dissolving, removing free radical and thrombus target/antithrombotic San Seed function Xin Ying compound Ji Qi System Prepare method and purposes. This Hair Ming Yi Even meets arm Will thrombus dissolving peptide, radicals scavenging Elixirs and thrombus target/antithrombotic Tai Group and is combined to form San Yuan Suffix conjunction object, obtains collecting Kua Xue Brain barrier, thrombus dissolving, the compound for removing the effects of free radical, thrombus target/antithrombotic Yu mono- Body. The bright It of this Hair is related to the Drug object Group containing the compound and closes object, wherein describedization closes object shape into Satisfied meters of ball structures. This Hair brightization closes the thrombus dissolving activity and thrombus target/antithrombotic acitivity for removing NO free radical activity, Gifted Iso of object Ju You More high. Anti- Que courage and uprightness Zhong Wind activity , Ke System Prepare of the bright compound It of this Hair with Gifted Iso blocks Pro Drug object at Zhi Treatment Brain.本發明涉及一種同時具有溶血栓、清除自由基和血栓靶向／抗血栓三種功能的新穎化合物及其製備方法和用途。本發明以連接臂將溶血栓肽、自由基清除劑和血栓靶向／抗血栓肽組合在一起形成三元綴合物，得到集跨血腦屏障、溶血栓、清除自由基、血栓靶向/抗血栓等作用於一體的所述化合物。本發明還涉及含有所述化合物的藥物組合物，其中所述化合物形成納米球結構。本發明化合物具有較高的清除NO自由基活性、優異的溶血栓活性和血栓靶向／抗血栓活性。本發明化合物還具有優異的抗缺血性中風活性，可製備成治療腦梗塞的臨床藥物。
