Andreas Jahn,Wyatt N. Vreeland,Laurie E. Locascio,Michael Gaitan
申请号:
US10895366
公开号:
US09198645B2
申请日:
2004.07.21
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Methods for the formation of liposomes that encapsulate reagents in a continuous 2-phase flow microfluidic network with precision control of size, for example, from 100 nm to 300 nm, by manipulation of liquid flow rates are described. By creating a solvent-aqueous interfacial region in a microfluidic format that is homogenous and controllable on the length scale of a liposome, fine control of liposome size and polydispersity can be achieved.