MedImmune, LLC;The Regents Of The University Of California
发明人:
Ronald James Christie,Changshou Gao,Andre Henri St. Amant,Javier Read de Alaniz
申请号：
US16615582
公开号：
US20200206359A1
申请日:
2018.05.25
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides a bioconjugation method and compounds for use therein. The bioconjugation method comprises the step of conjugating a biological molecule containing a first unsaturated functional group with a payload comprising a second unsaturated functional group, wherein the first and second unsaturated functional groups are complementary to each other such that conjugation is a reaction of said functional groups via a Diels-Alder reaction which forms a cyclohexene ring.
