Laskavy, Vladislav Nikolaevich;Ivlev, Andrei Valentinovich
发明人:
申请号：
EP17873383.8
公开号：
EP3403668A1
申请日:
2017.06.13
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The invention generally relates to the field of veterinary medicine and can be used for bovine leukemia prevention. The invention expands the range of means of the claimed application and provides lifelong resistance of animals to the leukemia virus.The invention is aimed at solving the problem of expanding the range of preventive medications and forming new approaches to the problem of preventing bovine leukemia, which allow ensuring lifelong resistance of the animals to leukemia infection.The technical result consists in the design of a remedy and use thereof for bovine leukemia prevention, which would allow providing a targeted immune response, efficiently and with minimal costs, by activating cellular immunity against bovine leukemia virus by increasing the number of killer cells.The remedy for bovine leukemia prevention contains a water-soluble protein fraction with a molecular weight of 18-20 kDa, isolated from the tuberculosis mycobacterium destruction products, characterized by the presence of peaks at a wavelength of 214 nm in the UV region, a phosphate-buffered saline, an aqueous formaldehyde solution, and an isotonic sodium chloride solution.The use consists in administering the said remedy to 1 to 9 day old calves with a single intramuscular injection at a dose of 4.0-6.0 ml per capita.
