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METHODS AND COMPOSITION FOR TREATMENT OF CARDIOVASCULAR CONDITIONS
专利权人:
发明人:
Joseph A. Fix,Shirish A. Shah,Pratibha S. Pilgaonkar,Anilkumar S. Gandhi
申请号:
US15154618
公开号:
US20170326065A1
申请日:
2016.05.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to methods for treatment of cardiovascular conditions selected from high blood pressure, heart failure, or heart attack. The present invention further relates to a method of treating cardiovascular conditions comprising orally administering once a day to a human subject in need thereof the compound valsartan in an extended release dosage form, wherein the ratio of mean plasma concentration of valsartan provided by the extended release dosage form to the mean plasma concentration of valsartan provided by an immediate release dosage form of valsartan over 8 hour to 24 hour period after administration is greater than 1 in a single dose human pharmacokinetic study.
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