VIRAL VECTORS ENCODING RECOMBINANT FIX VARIANTS WITH INCREASED EXPRESSION FOR GENE THERAPY OF HEMOPHILIA B

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专利权人:

BAXALTA INCORPORATED;BAXALTA GMBH

发明人:

HORLING, FRANZISKA,LENGLER, JOHANNES,FALKNER, FALKO-GUNTHER,ROTTENSTEINER, HANSPETER,SCHEIFLINGER, FRIEDRICH

申请号：

CA3064730

公开号：

CA3064730A1

申请日:

2018.05.22

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present disclosure provides, among other aspects, codon-altered polynucleotides encoding Factor IX variants for expression in mammalian cells. In some embodiments, the disclosure also provides mammalian gene therapy vectors and methods for treating hemophilia B.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/