STABILIZED SOLUTION BASED ON ACTIVE SUBSTANCES, METHOD FOR PRODUCING A STABILIZED SOLUTION OF ACTIVE SUBSTANCES, PHARMACEUTICAL COMPOSITION BASED ON A STABILIZED SOLUTION OF ACTIVE SUBSTANCES (OPTIONS)
This invention relates to pharmaceutical compositions (variants) based on a stabilized solution of two active ingredients, said stabilized solution of two active ingredients comprising, as first active ingredient, low-molecular weight hyaluronic acid and/or a pharmaceutically acceptable salt thereof, wherein the molecular mass of said acid or salt is from 100 kDa to 400 kDa or, in a variant, from 400 kDa to 2.5 MDa, and, as second active ingredient, Decametoxin or a water-soluble salt thereof, and a stabilizer in the form of a pharmaceutically acceptable salt that is capable of dissolving in water and dissociating in aqueous solutions into metal cations and acid residue anions, or a mixture of such salts, wherein the stabilizer is capable of forming water-soluble compounds with hyaluronic acid and/or a pharmaceutically acceptable salt thereof and Decametoxin or a water-soluble salt thereof, simultaneously. The stabilized solution further contains at least one pharmaceutically acceptable additive.
