The present invention relates to a recombinant L. lactis strain expressing GLP-1. The present invention further relates to the use of said recombinant L. lactis strain expressing GPL-1 in medicine, in particular in the treatment of diabetes. The present invention further relates to said recombinant L. lactis strain expressing GPL-1 wherein said recombinant L. lactis strain releases GLP-1 in the gut over a period of several days. The present invention further relates to compositions comprising said recombinant L. lactis strain expressing GPL-1 wherein the said composition is encapsulated to be predominantly released in the gut and to increase its shelf life. A food composition comprising a recombinant Lactococcus lactis strain is also claimed. The present invention further discloses a method for the preparation of said recombinant L. lactis strain expressing GLP-1 utilising the GLP-1 expression plasmid vector pUK200_glp1.
