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EXPRESSION DE GNTIII (UDP-N-ACETYLGLUCOSAMINE:BETA-D MANNOSIDE BETA (1,4)-N-ACETYLGLUCOSAMINYLTRANSFERASE III) DANS DES PLANTES
专利权人:
PLANT RESEARCH INTERNATIONAL B.V.
发明人:
BAKKER, HENDRIKUS ANTONIUS CORNELIS,FLORACK, DIONISIUS ELISABETH ANTONIUS,BOSCH, HENDRIK JAN
申请号:
CA2478294
公开号:
CA2478294C
申请日:
2003.03.18
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to the field of glycoprotein processing in transgenicplants used as cost efficient and contamination safe factories for theproduction of recombinant biopharmaceutical proteins or pharmaceuticalcompositions comprising these glycoproteins. The invention provides a plantcomprising a functional mammalian enzyme providing mammalian GnTII (EC2.4.1.144)l that is normally not present in plants, said plant additionallycomprising at least a second mammalian protein or functional fragment thereofthat is normally not present in plants.
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