BETAGERI GURU V,AGNIHOTRI SUNIL A,SOPPIMATH KUMARESH
申请号:
IN3796/DELNP/2013
公开号:
IN2013DN03796A
申请日:
2013.04.30
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
The invention relates to a novel free flowing powder pharmaceutical formulation for the delivery of a poorly water soluble drug substance that increases the solubility and bioavailability of the poorly water soluble drug substance as well as to a method of making the free flowing powder pharmaceutical formulation. The invention also relates to dispersed particles that disperse instantaneously from the free flowing powder formulation when the formulation is added to water aqueous solvent or organic solvent wherein the bulk distribution of the poorly water soluble drug substance of the free flowing powder formulation in the dispersed particles is uniform. Such dispersed particles increase the bioavailable surface area of the poorly water soluble drug substance and facilitate the drug substance s dissolution.