The present invention relates to an antibody-drug conjugate (ADC) and to acomposition containing thisconjugate for use for the treatment of cancer. The present invention provides,with respect to an ADC between a drug andan antibody specific for insoluble fibrin, an ADC wherein the linkerconnecting the antibody and the drug has a plasmincleavage site, and also provides a pharmaceutical composition containing thisADC for use for the treatment of cancer.