DONG, QING,GONG, XIANCHANG,KALDOR, STEPHEN W.,KANOUNI, TOUFIKE,SCORAH, NICHOLAS,WALLACE, MICHAEL B.,ZHOU, FENG
申请号:
MYPI 20092545
公开号:
MY157871A
申请日:
2007.12.18
申请国别(地区):
MY
年份:
2016
代理人:
摘要:
2 1 2 ABSTRACT MEK-5004-WO MAPK/ERK KINASE INHIBITORS [04161 COMPOUNDS OF THE FOLLOWING FORMULA ARE PROVIDED FOR USE WITH MEK: R2 @'RJ R3,@ )@ "@L N X XI X 5 X3,@ -,@-X2 N N I I R4 K5 WHEREIN THE VARIABLES ARE AS DEFINED HEREIN. ALSO PROVIDED ARE PHARMACEUTICAL 5 COMPOSITIONS, KITS AND ARTICLES OF MANUFACTURE COMPRISING SUCH COMPOUNDS; METHODS AND INTERMEDIATES USEFUL FOR MAKING THE COMPOUNDS; AND METHODS OF USING SAID COMPOUNDS.