An imaging device, an endoscope, an endoscope system, and a method for driving an imaging device capable of reducing power consumption are provided. The imaging device includes: a first chip 21 having a plurality of pixels that generates and outputs an imaging signal a transmission cable 3 connected to the first chip 21 and configured to propagate the imaging signal a terminating resistor 51 provided at a terminal of the transmission cable 3, including an alternating current terminating resistor 502 with variable resistance and a direct current terminating resistor 501 with variable resistance, and having a constant combined resistance of the direct current terminating resistor 501 and the alternating current terminating resistor 502, and a control unit 55 configured to perform control to make a resistance of the direct current terminating resistor 501 during a blanking period in which the first chip 21 does not output the imaging signal higher than that during the normal operation period in which the first chip 21 outputs the imaging signal, so that current output by the first chip 21 is suppressed.