Carboxamide derivatives useful as RSK inhibitors

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专利权人:

Phoenix Molecular Designs

发明人:

Dunn, Sandra E.,Jayanthan, Aarthi,Nagireddy, Jaipal Reddy,Annedi, Subhash,Van Drie, John H.,Daynard, Timothy S.,Huynh, My-My

申请号：

AU2017220738

公开号：

AU2017220738A1

申请日:

2017.02.17

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity. Such carboxamide derivatives form bicyclic and tricyclic ring systems and the disease or condition associated with RSK activity in a mammal is cancer.

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