PROBLEM TO BE SOLVED: To select an optimal anticholinergic agent to be compounded to an excellent antipyretic analgesic anti-inflammatory agent containing loxoprofen and caffeine for further getting the effect of suppressing snivel (excessive nasal drip).SOLUTION: There is provided a pharmaceutical composition containing (a) loxoprofen, (b) caffeine and (c) belladonna extract or belladonna total alkaloids, and developed based on a finding that belladonnas are most suitable as an anticholinergic agent.COPYRIGHT: (C)2014,JPO&INPIT【課題】ロキソプロフェンとカフェインを含有する優れた解熱鎮痛消炎剤組成物に、更に、鼻水(鼻汁過多)の効果を得る目的で配合するための至適抗コリン剤を選定すること。【解決手段】抗コリン剤として、ベラドンナ類が至適であることを見出した。【選択図】なし