Hyung Won RYU,In-sik SHIN,Hyuk-hwan SONG,Su Ui LEE,Hyeong-kyu LEE,Kyung-seop AHN,Sei-ryang OH,Byung-hwan RYOO,Dae-hee SHIN,Ji-seok YOO,Yongnam LEE
申请号：
MX2017000991
公开号：
MX2017000991A
申请日:
2015.07.22
申请国别(地区):
MX
年份:
2017
代理人:
摘要：
The present invention relates to a novel methanocyclopenta[e][1,3]dioxepin-7-yl 3,4-dihydroxybenzoate derivative (KS534) represented below as the Chemical Formula 1, the pharmaceutically acceptable salt or solvates thereof, a composition comprising the same as an active ingredient for preventing or treating allergic disease, inflammatory disease, asthma or chronic obstructive pulmonary disease (COPD) and the use thereof. Formula (1).La presente invencion se relaciona con un (3R,5S,5aS,6R,7S,8R,8aS) -8-cloro-8ª hidroxi-5-(2- hidroxi acetoxi)hexahidro-1H-3,6-metanoc iclopenta[e][1,3]dioxepin-7-il 3,4-dihidroxibenzoato (KS534), el isomero de este, la sal o solvatos farmaceuticamente aceptables de este, una composicion que comprende el mismo como un ingrediente activo para la prevencion o tratamiento de la enfermedad alergica, la enfermedad inflamatoria, el asma o la enfermedad pulmonar obstructiva cronica (COPD) y su uso.
