An electrotherapy device capable of gradually increasing the intensity of stimulation is provided with a voltage regulation circuit, which is electrically connected to a DC power supply unit, a control unit, and a pulse output circuit respectively, and can regulate the voltage output to the pulse output circuit according to a control signal received from the control unit, in order for the waveforms of the electrical pulses output from the pulse output circuit to vary in modulated intensity, modulated waveforms, modulated frequencies and modulated rest period durations, and for the output current output from the pulse output circuit to each electrode pad to gradually increase from a low value to a predetermined value. The electrotherapy device can thus stimulate corresponding acupoints on a human body with gradually increasing intensity and thereby simulate the forces and tactile sensations of a typical manual massage on those acupoints by hand.