1. Use of 10 - [(3R) -1-azabicyclo [2.2.2] oct-3-ylmethyl] -10H-phenothiazine, 10 - [(3R) -1-azabicyclo [2.2.2] oct-3-ylmethyl] -10H-phenothiazine or 10 - [(3R, 3S) -1-azabicyclo [2.2.2] oct-3-ylmethyl] -10H-phenothiazine or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the prevention or treatment of pathologies in which H4 is involved a histamine receptor selected from: atopic dermatitis, pruritus, or bronchial inflammation, such as asthma and obstructive bronchopneumopathy. ! 2. The use according to claim 1, characterized in that the drug is 10 - [(3S) -1-azabicyclo [2.2.2] oct-3-ylmethyl] -10H-phenothiazine. ! 3. The use according to claim 1, characterized in that the drug is 10 - [(3R) -1-azabicyclo [2.2.2] oct-3-ylmethyl] -10H-phenothiazine. ! 4. The use according to claim 1, characterized in that the drug is presented in a form suitable for oral administration, and contains an amount of the active ingredient sufficient to antagonize the target H4 histamine receptors. ! 5. The use according to claim 4, characterized in that the drug is presented in oral dosage form, providing a dose of administration from 1 μg / kg to 10 mg / kg, preferably from 0.01 mg / kg to 1 mg / kg. ! 6. The use according to claim 4 or 5, characterized in that the drug is presented in tablet form. ! 7. The use according to claim 4 or 5, characterized in that the drug is in the form of a solution for oral spray or powder for inhalation, in particular suitable for the treatment of asthma or obstructive bronchopneumopathy. ! 8. The use according to claim 1, characterized in that the drug is intended to prevent or treat pathologies in which H4 histamine receptors and muscarinic receptors are involved1. Применение 10-[(3R)-1-азабицикло[2.2.2]окт-3-илметил]-10H-фенотиазина, 10-[(3S)-1-азабицикло[2.2.2]окт-3-илметил]-10H-фенотиазина или 10-[(3R,3S)-1-азабицикло[2.2.2]окт-3-илметил]-10H-фенотиазина или его фармацевтически приемлемой соли для получения лекарств
