ENHANCED PRODUCTION OF RECOMBINANT CRM197 IN E. COLI

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专利权人:

Scarab Genomics; LLC

发明人:

BLATTNER, Cristopher, R.,FRISCH, David, A.,NOVY, Robert, E.,HENKER, Terrance, M.,STEFFEN, Eric, A.,BLATTNER, Frederick, R.,CHOI, Hyunsic,POSFAI, Gyorgy,LANDRY, Charles, F.

申请号：

EP15758620

公开号：

EP3113800A4

申请日:

2015.03.02

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Rediced genome or native K12 strain E. coli bacteria comprising expression vectors encoding a recombinant CRM197 protein and their use in the production of CRM 197 is provided. The CRM 197 protein may be fused to a signal sequence that directs the expressed CRM197 protein to the periplasm of the E. coli host.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/