Koteppa Pari,Girish Badrinath Mahajan,Nidhi Tomar,Vijaya Phani Kumar Yemparala,Asha Adrian Kulkarni-Almeida,Saji George
申请号：
US13012463
公开号：
US08263579B2
申请日:
2011.01.24
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention relates to novel compounds obtained by fermentation of Myxobacteria strain (PM0670013/MTCC 5570). The present invention further relates to the processes for the production of the novel anti-inflammatory compounds, to the culture no. PM0670013 (MTCC 5570), and to pharmaceutical compositions containing compounds of the present invention as an active ingredient and its use in medicines for the treatment of inflammatory diseases or disorders mediated by proinflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-α) and/or interleukins such as IL-6, having anti-inflammatory activity The invention also includes all stereoisomeric forms of compounds of the present invention.
