VLP-BASED MONOVALENT EBOLA VACCINES AND METHODS OF MAKING AND USING SAME

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专利权人:

Xuemin CHEN;Children's Hospital Medical Center

发明人:

Xuemin Chen,Karnail Singh,Paul Spearman

申请号：

US16494843

公开号：

US20200085937A1

申请日:

2018.03.28

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Disclosed herein are virus-like particle (VLP)-based monovalent vaccine compositions. The compositions may comprise a spherical retroviral Group-specific Antigen (“Gag”) protein core and a single Ebola glycoprotein selected from either a Zaire (EBOV) glycoprotein or a Sudan (SUDV) glycoprotein. The Ebola glycoprotein may be incorporated into the surface of the spherical Gag core, wherein said VLP-based vaccine presents a single Ebola glycoprotein antigen.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/