The present invention relates to a method of preparing sustained-release drug microparticles allowing easy release control. According to the method of the present invention, as can be seen in Examples of the present invention, an initial release amount may be easily controlled by simply adjusting the evaporation temperature of a solvent in a conventional method of preparing microparticles. In addition, since no additional process is required, a drug loading rate may be significantly increased, and since high temperature is not required, the stability of a drug that is weak to heat may be ensured.